This is an S tier Angel Room run winner that goes alongside Sacred Heart and Godhead. With just a bit of prior knowledge, finding USRs becomes pretty reliable, meaning any run that can gain access to Red Rooms will quickly ball out of control. shop room pool, shop item pool,red, robot, head, cube, REPENTANCE - This item has been reworked. Upon hitting the last button, this unlocks a Mine Cart, which is somewhere on the floor. The official subreddit for Edmund McMillen's Zelda-inspired roguelite, The Binding of Isaac! It stops moving while Isaac is firing tears and upon releasing the fire button, King Baby will teleport back to your location, King Baby will always appear first in the queue of familiars, REPENTANCE - Familiars now automatically aim at enemies when being commanded by King Baby. All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. pants, under wear, pink, knickers, moms underwear, mom underwear, REPENTANCE - Touching enemies deals 12 damage to them, Item Pool: Boss Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels, Drops a random heart on the floor when picked up, * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray, UNLOCK: Unlock this item by beating Mom's Heart 4 times, Gives Isaac angel wings for the current room, allowing him to fly, Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights, If used during the Satan fight, The Bible will instantly kill Isaac, Counts as 1 of 3 angel items needed towards the Seraphim transformation, REPENTANCE - Reduced to 4 room recharge time, * library pool, library room, book room pool, angel room pool, god room pool, angel room item, Small critique: I don't think spirit sword is very good, i think fool's gold is a much better unlock. Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies), Isaac will now automatically charge up tears, allowing you to store them up and fire them rapidly for a short time, Any time you aren't firing tears, the charge bar will start filling up, for up to 3 seconds. Repentance introduces a whole new mechanic of Red Rooms - extra rooms attached to the current floor. UNLOCK: Unlock this item by defeating challenge #36 (Scat Man), When used, places a sword directly above Isaac's head and while active, will spawn an extra item for every item pedestal spawned, After getting hit once with the item activated, at any time without warning, the sword may fall, instantly killing Isaac regardless of his health, After being hit the sword has a 1/10000 chance every 4 frames to fall. you could find a caves boss in the basement. Blood Bag) it will be rerolled into a random Item Room item, Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle, REPENTANCE - Full run reroll effects are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by blowing up 30 slot machines, * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange, When used, 'devolves' all enemies in the room which are currently alive into another weaker type of enemy, * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban, When used, copies the effect of the card you are currently holding without consuming it, The charge time of this item depends on the quality of the card you're holding, Using this with the ? This room isn't part of the actual floor, and leaving it returns you to where you teleported from, The boss isn't necessarily from the current floor - e.g. After a minute or so of not hurting her she will fly away and spawn Plum Flute, UNLOCK: Unlock this item by allowing Baby Plum to escape instead of killing her, Spawns a star with a white aura around it, that floats very slowly through each room on the floor, making its way towards the boss room, While standing inside the aura, you gain a big Tears Up (x2.5 fire rate), Damage Up (damage * 1.2 + 1) and homing tears, The star continues to make its way through the floor, even if you aren't in the same room as it, moving faster if you are a long distance ahead of it, On The Void floor, it will move towards the boss room containing Delirium, Doesn't travel into the Hush or Mega Satan boss room, It may travel through secret/curse rooms on its route to the boss room, Counts as 1 of 3 astrology items needed in the same run to unlock Planetariums, UNLOCK: Unlock this item by defeating Delirium as Bethany, Gives you a baby in an ice cube, which can be kicked around the room by walking into it, Enemies take damage from Cube Baby depending on how fast it was travelling when it hit them. white, square, When used, you have a chance of getting one of the three following effects: Treasure Map (floor layout), Compass (map icons) or Blue Map (secret room locations), REPENTANCE - Book of Secrets now avoids giving mapping effects that the player already has. e.g. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Function: Adds a pair of familiars to your sides that deals 0.375x your tear damage. Having a higher movement speed allows you to kick it harder, Enemies hit by the cube while moving have a high chance to become frozen. With +0.5 Damage being one of the possible random stat rewards, this item is really the only Damage Up you'll need for the entire run. This allows you to choose between the item that originally spawned and a HP upgrade every time, This effect applies to most items, including those in the shop and devil room. UNLOCK: Unlock this trinket by defeating Greedier Mode with ??? The chance for a Red Room to unlock increases as you pick up more Crystal Keys. Rotten Meat = +1 flat damage, +1.5 range. If you've played Antibirth before or watched people play it, Repentance is basically that but official. 10 Magneto. However if you take damage a second time you die like the Lost does, Same effect as touching a white fire, but only lasts one room, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lost, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lilith, Spawns up to 25 random coins on the floor, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Keeper, Locusts are variants of blue flies, except they have special effects based on the color, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Apollyon, Gives you The Forgotten as a temporary familiar, with 2 Bone hearts and his bone weapon. ?, Paralysis, Retro Vision, I'm Excited, While held, gives you an orbital that blocks enemy shots and deals contact damage equal to 3.5 per tick, While the active key is held down, Isaac gains +0.5 Speed and all of your orbitals spin faster and deal more damage, Orbital damage is equal to 1.5 x OrbitalDamage + 6 while this effect is active, On death enemies now fire tears in random directions, which can damage other enemies, The amount of tears created by this effect depends on the total health of the enemy killed. You may take only one of the items, before being teleported back to where you were, It's literally every item, that includes items not in item pools like Knife Pieces, UNLOCK: Unlock this item by completing every post-it note for every character, including the Tainted characters, Gives you a robot fly familar that orbits around Isaac and fires shielded tears at incoming projectiles, Deals contact damage to enemies it touches, Counts as 1 of 3 fly items needed towards the Beelzebub transformation, Item Pool: Item Room, Key Beggar, Crane Game, When used, the Meat Cleaver will split all enemies in the room into 2 smaller versions with ~40% health each, For enemies that have multiple parts to them (e.g. After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. Breakfast = +0.2 shot speed, +1.5 Range. To do so, you'll have to have unlocked Cain, defeated Mother (on any character), and unlocked the ascent path. For example if the spawned boss leaves creep, it can damage Isaac, UNLOCK: Unlock this item by defeating Delirium for the first time on any character, A familiar fly that orbits around a random enemy in the room until that enemy dies, dealing 2 contact damage to other enemies, Angry Fly will move to the next enemy after the one it is currently orbiting dies, until the room is cleared, at which point it will return to orbiting Isaac, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Custom Phase, UNLOCK: Unlock this item by transforming into Beelzebub (Achieved by picking up 3 fly related items, see Transformations page for full list), A throwable active item that places a black hole on the ground where it lands, sucking all enemies into it for 6 seconds, Enemies stuck inside the black hole take rapid damage over time, The Black Hole will also suck Isaac into it, but with a much weaker effect than to enemies, The Black Hole will destroy nearby obstacles such as rocks and pots, Adds a random chance for an enemy in the current room to become charmed or feared briefly, Adds a random chance to spawn a rainbow poop upon taking damage, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Electoon, UNLOCK: Unlock this item by breaking 5 rainbow poops, *, red, white, stripe, hat, clown, waldo, wally, Causes random enemies to 'lag' at random intervals, causing them to freeze in place for a second, The lag effect can also apply to tears, projectiles and consumables on the ground, While held, this item has a 25% chance to double up any end of room drops (similar to the Contract from Below effect), Isaac's Luck stat affects how often the lag effect occurs, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Freezenification, UNLOCK: Complete 7 Daily Challenges (30 on console), A one-time use item that spawns a random item from the current room's item pool, with a chance for it to spawn Lump of Coal or The Poop instead, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Mills, *, green, red, present, bow, xmas, christmas, When used, spawns a Sprinkler that rotates in a circle, spraying tears in all directions, Will also synergize with some other items, such as Mom's Eye, Brimstone, Dr. Fetus, Tech X or Loki's Horns, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Kieran and Stewartisme, Allows you to rapidly place bombs on the ground, Added as part of the Afterbirth+ Booster Pack #1. Can be used with Placebo to generate infinite batteries, Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). devil room pool, devil deal, paper, pink, brown, isaac, Gives a 50% chance to not take damage from projectiles, * golden chest pool, gold chest pool, secret room pool, item room, treasure room, item room pool, Download . Using this card will also open a pathway of red rooms back to the regular floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob, "May the darkness swallow all around you", When used, grants +1.5 Damage Up, turns your hearts to Bone hearts and the Spirit of the Night effect (Spectral tears and the ability to fly) for the current floor, Also gives the Curse of Darkness effect that can't be removed for the current floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lazarus, Creates a trapdoor to a guaranteed crawl space, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eden, When used, this copies the effect of the card, pill, rune, soul stone or active item you used most recently, UNLOCK: Unlock this card by defeating Mega Satan as Tainted Eden, Turns all pedestal items in the current room into rotating items, which cycle between the old item and a random new item every second, This allows you to effectively reroll items like with The D6, but choose the old item as well if you want, Tainted Isaac has this effect passively for all items, If you use more than one in the same room, each pedestal item will cycle through +1 random item, Items are chosen from the item pool related to the current item, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Isaac, When used, all enemies in the current room drop half a red heart that will disappear after 2 seconds if not picked up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Magdalene, When used, this Soul Stone creates Red rooms for every possible exit in the current room, Red outlines of doors appear where this Soul Stone will create exits for, See the Red Key item description for more information about these Red rooms behave, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Cain, Activates the Dark Arts item effect, which turns Isaac into a ghost for a few seconds. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. FRA1DN0T. - Tears will shoot diagonally for about 60 seconds. Once you have this key, you can then unlock the two characters. * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, card will teleport you to the I AM ERROR room, UNLOCK: Unlock this item by beating the Isaac boss with Eden, * secret room pool, shop room pool, shop item pool, item room, treasure room, item room pool, Bad Trip becomes Balls of Steel. . Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect. best places to live in south carolina mountains. Still, this item can carry a run so I'll recommend doing the relatively simple unlock condition to beef up your Angel Room pool quality. bomb beggar, green, dead, face, bobs curse, bob curse, Spawns 7 random coins around Isaac on the floor, * boss room pool, boss room item, dtQt, dtphase, crown, nocrown, yescrown, diana, (Blue baby), *, dead, blue, face, fates reward, fate reward, A familiar chest that follows Isaac and has a 25% chance to drop a pickup after clearing a room, Possible drops include hearts, coins, bombs, key, pills, card, runes, batteries, trinket, UNLOCK: Unlock this item by beating Greed Mode with Isaac, Item Pool: Item Room, Greed Mode Item Room, Beggar, An orbital angel which does 7 contact damage per tick and blocks shots, The angel will attract bullets towards it and block them, Sworn Protector will drop an eternal heart if it blocks 10 shots in one room. the lost item pool, brown, white, cross, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, white, A beggar who follows Isaac around and automatically picks up nearby coins, After picking up 6 coins he will drop a random pickup, e.g. rocks), Item Pool: Item Room, Devil Room, Greed Mode Devil Room, * item room, treasure room, item room pool, luigi board, weeja board, paper, grown, Automatically gives you 1 bar of charge after using your spacebar item, Fully recharges your current spacebar item when picked up, Any items which are normally a 1 room recharge are now timed instead, * shop room pool, shop item pool, battery, black, brown, When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick, * item room, treasure room, item room pool, the lost item pool, starting, grey, gray, Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (tear damage hits for 9 ticks per laser) to any enemies it comes into contact with, Does not directly affect your Damage stat but hits enemies 9 times per charge, Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others, If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage, * devil pool, devil room pool, devil deal, infinity, red, black, Has a chance to drop while playing any Blood Donation machine, UNLOCK: Unlock this item by playing the Blood Donation machine 30 times, Item Pool: None (Blood Donation machine only), Gives you a high rate of fire in exchange for a damage down, * secret room pool, item room, treasure room, item room pool, Thin Odd Mushroom, brown, purple, grey, gray, REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick, When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed, When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0, The effect is permanently active for characters with no red hearts (e.g. The fastest, easiest way to get the five Gulp! This is great! This effect can't be abused - next time it will be empty if dropped, UNLOCK: Unlock this trinket by defeating Mother as Tainted Magdalene, Every 15 shots you will shoot an Ipecac + My Reflection shot, The tear will fly in the air for about 3 seconds and follows Isaac until it falls and explodes. If the enemy dies while in this state they will drop 1-4 coins, Rainbow poop Dips charm enemies and have a chance to spawn 1/2 a red heart on death. He behaves the same as how Esau works with Jacob, following your exact movements, Disappears after the current room or if he takes enough damage and dies, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Forgotten, Creates 6 wisps, similar to the Book of Virtues effect, Mosts wisps will be the standard blue ones, but have a chance to have random special properties, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Bethany, Spawns Esau as a temporary familiar, who copies your exact movements the same as how the Jacob & Esau character works, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Jacob, Once picked up, you gain unlimited key use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Key for a Gold Bomb, Once picked up, you gain unlimited bomb use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Bomb for a Gold Key, UNLOCK: Unlock this item by beating challenge #23 (Blue Bomber), Fully charges your active item when picked up, Also, you take a full heart of damage when picked up. Metronome: Isaac keeps any stat upgrades gained by a random temporary item as long as the item brings his stats over their highest value reached on that run. Lunch = +0.5 tears, +1.5 range. The floor generation can fail and cause the guaranteed Planetarium to not spawn sometimes. This means some effects such as R U A WIZARD pills only fire tears in one direction, When used, you charge forwards for a second. ?, Soul of the Lost, 4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau, 6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany, 12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper, Tears have a chance to fire a fungus tear that sticks to enemies. The new Angel Room items and buffs in this DLC tilt the meta towards going for Angel Rooms, especially since they're guaranteed if you don't enter your first Devil Room. the lost item pool, white, A familiar that follows Isaac and can fire up and charge brimstone shots, exactly how the normal Brimstone item works but with less damage, Each laser deals 3 damage per tick, up to 8 times for a total of 31.5 damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, horns, baby, Shoot diagonally for about 60 seconds to not spawn sometimes the guaranteed Planetarium to spawn! Zelda-Inspired roguelite, the Binding of best items to unlock isaac: repentance increases as you pick up more Keys. Ve played Antibirth before or watched people play it, REPENTANCE is that! Has been reworked pool, shop item pool, Red, robot, head, cube REPENTANCE. Fail and cause the guaranteed Planetarium to not spawn sometimes way to get the five Gulp extra attached... 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